Alimentary System
С.Ж.АСФЕНДИЯРОВ АТЫНДАҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕДИЦИНА УНИВЕРСИТЕТІ |
КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д.АСФЕНДИЯРОВА | |
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Тheme : «Alimentary System.»
Alimentary System
The alimentary system (Lt. alimentum :
- oral cavity
- pharynx
- oesophagus
- stomach
- small intestine
- large intestine
- anus
The gastrointestinal system is (strictly speaking) composed of only the stomach and small and large intestines but is commonly deemed to include the oesophagus as well.
A knowledge of the normal microanatomy of the gastrointestinal system is vital to the understanding of:
- the normal function of the gastrointestinal system
- the pathology of gastrointestinal disease
- staging of gastrointestinal tumours
Normal function of the gastrointestinal system
The main functions of the gastrointestinal system are:
- absorption of nutrients from ingested food
- protection against ingested pathogens
Absorption of nutrients from ingested food occurs in four main phases within defined regions of the gastrointestinal tract
1. fragmentation
- starts in the oral cavity, continues in the stomach
- aided by secretion of saliva from salivary glands
2. digestion
- starts in the stomach, continues in the duodenum
- aided by pancreatic enzymes, bile salts, brush border enzymes
3. absorption
- occurs mainly in the jejunum and ileum
- aided by the large surface area produced by mucosal villi and microvilli
- absorbed nutrients are transported away from the mucosa via lacteals and capillaries
4. elimination of waste products
- liquid residue passes into the large intestine where water is progressively absorbed from it
- resultant solid faeces are expelled through the anal canal
In order for food to be properly absorbed, it must be propelled smoothly from one segment to another. This occurs via:
- voluntary muscular action
- striated muscle in the oral cavity, pharynx and upper oesophagus
- involuntary muscle contraction (peristalsis)
- smooth muscle of the muscularis propria
- modulated by autonomic nerves in the submucosal and myenteric plexuses
Protection against ingested pathogens occurs as a result of
- lymphoid aggregates distributed throughout the gastrointestinal tract (mucosa-associated lymphoid tissue or MALT)
- IgA secreted into the gut lumen
Structure of the gastrointestinal
system
The gastrointestinal system (or tract) is essentially a muscular tube
which has the same basic structure throughout. Four layers are recognised,
from inside out:
- mucosa
- submucosa
- muscularis propria
- serosa
The mucosa varies greatly in the different regions of the gastrointestinal tract while the other layers are essentially the same.
Structure of GI tract
Mucosa
- is composed of
- epithelium
- lamina propria (loose connective tissue)
- muscularis mucosae (thin layer of smooth muscle)
- changes abruptly from one type to another at several points along the tract
Submucosa
- is composed of fairly dense connective tissue containing blood vessels, lymphatics and nerves
Muscularis propria
- is divided into two layers
- inner circular layer
- outer longitudinal layer
- has inherent rhythmicity which results in peristalsis

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